About 92.1 million adults living in America have some form of heart disease. A total cost of more than $329.7 billion is attributed to the disease according to The American Heart Association.
By 2030 the number of deaths due to cardiovascular disease is expected to be more than 23 million.
What happens to the heart with age?
The blood vessels that supply blood to the heart grow stiff with age.
Oxidative stress generates free radicals that damage certain cells in the organ and the vessels, and blood vessels get clogged or build up plaque.The impairment results in various symptoms.
During youth, bodies produce enough antioxidants to quench those free radicals.
But with age, the balance tips, as mitochondria and other cellular processes produce excess free radicals, and the body's antioxidant defenses can't keep up.
The vessels get clogged and this results in conditions such as hypertension.
Plaque can build up and limit blood flow due to a condition called atherosclerosis. The buildup is caused due to various substances such as fat and cholesterol, among others, collecting in the arteries.
It can occur in any artery of the body, including the carotid, which supplies blood to the brain, coronary arteries and the aorta, which carries oxygenated blood from the heart through the abdomen to the rest of body.
"We don't usually worry too much about heart disease risk until a person is in middle age because it's rare to have a heart attack in young adulthood," said Pletcher, who is an associate professor of Epidemiology & Biostatistics and of Medicine at UCSF. "However, our evidence shows that young adulthood is an important time because lasting damage already starts to accumulate at this age."
How can I reduce the impact of aging on heart health?
Heart disease and stroke has a correlation with the levels of cholesterol throughout our life.
Modest increases in LDL (low density lipoprotein) has been shown to increase the risk of atherosclerosis.
Check cholesterol levels as early as 20 years old. Suboptimal levels of LDL increases risk of heart disease and stroke.
Coronary artery calcium, typically measured through a CT scan, is indicative of plaque buildup in the coronary arteries.
Atherosclerosis, or blockages in the coronary artery from cholesterol and plaque, can lead to heart attack and stroke.
According to the American Heart Association, the current medical guideline for heart disease is to check cholesterol levels at age 20, and to treat young adults only if they have extremely high cholesterol.
Why does energy-production enzyme in the cell decline?
In patients with congestive heart failure, myocardial Coenzyme Q10, also known as ubiquinone or CoQ10, content tends to decline as the degree of heart failure worsens.
Since CoQ10 levels are depleted by aging and statin medications and tend to be low in congestive heart failure, achieving optimal blood levels in CoQ10 can be an important strategy to protect heart health.
A number of controlled pilot trials with supplemental CoQ10 in heart failure found improvements in functional parameters such as ejection fraction, stroke volume and cardiac output, without side effects.
Recently, long-term therapy with coenzyme Q10 (CoQ10) has been shown to improve heart failure symptoms, reduce major adverse cardiovascular events (MACE) and mortality, and is considered to be safe and well tolerated.
Supplemental CoQ10 may be a useful option for effective management of heart failure, with the advantage of excellent clinical tolerance.
In an analysis of various CoQ10, the highest bio-availability being shown for soybean oil suspension of CoQ10 (Weis et al).
CoQ10 has garnered its status as an essential physiological cofactor. In addition to its central role in the production of cellular energy, CoQ10 can do some of its best antioxidant work in mitochondria.
In fact, CoQ10 is concentrated right in mitochondria to counteract the free oxygen ( rust ) produced during energy production.
What is CoQ10?
CoQ10 plays an important role in the synthesis of mitochondrial ATP and acts as an antioxidant in the mitochondria .
CoQ10, a vitamin-like nutrient, is naturally produced in the body and is an important part of energy generation and anti-oxidative conservation
CoQ10 is a natural antioxidant that can be found in many foods and is available as a supplement .
What can we do to help improve heart health?
Exercise and eating a healthy diet are the most well-established approaches for maintaining cardiovascular health.
However when looking for complementary, evidence-based options to prevent age-related changes that drive disease. CoQ10 supplements may be among them.
Studies, funded by the National Institue of Aging, have shown that CoQ10 is a stronger antioxidant than Vitamin E in preventing the oxidation of LDL cholesterol.
CoQ10 is classified as an antioxidant that helps to protect your body from damage caused by free radicals.
Antioxidants such as CoQ10 and vitamin C help stimulate cell health by neutralising harmful free radicals .
What else is CoQ10 involved with?
CoQ10 is also involved in the prevention of atherosclerosis, abnormal protein synthesis and degenerative diseases.
Due to its antioxidant activity, the effect on energy production and the ability to prevent blood clots, researchers believe that CoQ10 can help in conditions such as heart disease, immune function, diabetes, cognition and even migraines.